Django is a high-level Python Web framework that work with large-scale data-driven web applications and encourages rapid development and clean, pragmatic design.
Web2Py is full-stack python web framework for building scalable, secure and portable web applications.
Framework in Python that work with flexible configuration and extension and provide scalable web application
Pyramid web framework to develop web application framework technology in Python. Rather than focusing on a single web framework, the Pyramid Project will develop a collection of related technologies.
Asterisk is an open source telephony switching & private branch exchange service for developing scalable & secure VOIP system
Zope is a Python-based framework for creating secure & scalable web applications.
Flask is lightweight Python web framework based on Werkzeug and Jinja 2 that provide secure web applications
Cloud computing platform for building & hosting applications in Google managed data centers, GAE support all the framework (Django, Web2py, Cherrypy & Pyramid) wirtten in Python, With the GAE you can bundle a framwork for building secure & scalable web applications in Google managed data centers